Venient Cx Health Check Advanced - Female

Test Description
Venient Cx Health Check Advanced is a non-invasive test (only requires blood and urine samples) for a comprehensive assessment of major complex functions, body systems and the whole metabolism given that many diseases or pathologies have a multifaceted component that makes them sometimes difficult to diagnose. It is based on a routine blood and urine analysis and it is powered by both public and proprietary machine learning (ML) algorithms and checks up to multiple non-malignant diseases linked to the major complex functions, body systems and the whole metabolism, with the highest prevalence in the population, many of which are considered risk factors for cancer. This test calculates and quantifies the onset of some diseases years in advance, based on the results of clinical data, laboratory tests and lifestyle habits. Thanks to the information provided on a personalized basis, the extensive report will suggest the best option to take corrective measures to avoid the natural course of both non-malignant diseases and cancer. The Venient Cx Health Check Advanced test covers: hematologic system (erythrocytes and iron transport function; iron storage function; immune cells system; and platelet function), cardiovascular system (anthropometric indicators; atherogenic indices, and vascular age), endocrinologic system (glucose metabolism and pancreatic endocrine function, thyroid function and hypothalamic-pituitary axis); gastrointestinal tract (including colorectal health) and liver (including bile-pancreatic exocrine function); and genitourinary system (renal function; hydroelectrolytic metabolism; uric acid metabolism).

United States Preventative Services Task Force (USPSTF) screening recommendations
Currently, there is no USPSTF (United States Preventative Services Task Force) recommendation for "all medical" screening, and there is no commercially available FDA-cleared solution in the market.

Intended Use
Non-overweight women aged 40 onwards, annually and overweight or obese women aged 30 onwards, annually.

Sample Clinical Vignette
A 40-year-old female with sedentary lifestyle, smoker with an accumulated dose of 15 packs/year, high carbohydrates and fat diet, and several cardiovascular risk factors in first-degree relatives, presented for general check-up.

Required Laboratory Determinations
Hemogram —Red Blood Cell Count, Hemoglobin, Hematocrit—; Red Blood Cell Indices —Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Red Cell Blood Distribution Width (RDW)—; Leukocyte Count —Total Leukocytes Absolute, Total Neutrophil Absolute, Total Lymphocyte Absolute, Total Monocyte Absolute, Total Eosinophil Absolute, Total Basophil Absolute—; Platelets —Total Platelet Count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW)—; Serum Electrolytes —Calcium, Chloride, Magnesium, Phosphate, Potassium, Sodium—; Serum Proteins —Albumin, High Sensitivity C-Reactive Protein (hs-CRP)—; Serum Hepatic Enzymes —Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Gamma Glutamyl Transferase (GGT), Lactate Dehydrogenase (LDH)—; Serum Sterols & Fatty Acids —Total Cholesterol, HDL-Cholesterol, Cholesterol non-HDL, LDL-Cholesterol, VLDL-Cholesterol, Triglycerides—; Serum Hormones —Insulin, Thyroid-Stimulating Hormone (TSH), Thyroxine Free (T4 Free)—; Serum Other Serum Analytes —Bilirubin Total, Bilirubin Direct, Bilirubin Indirect, Serum Creatinine, Glucose, Serum Iron, Urea, Blood Urea Nitrogen, Uric Acid—; Other Urine Analytes —Urine Albumin, Urine Creatinine—; Urinalysis —Density, pH, White Blood Cells, Nitrites, Protein, Glucose, Urobilinogen, Urobilin, Red Blood Cells, Urine Sediment—.