Venient Fx Hydroelectrolytic Metabolism Comprehensive
Test Description
Venient Fx Hydroelectrolytic Metabolism Comprehensive is a disruptive, non-invasive test that provides comprehensive information on electrolyte balance (also known as hydroelectrolyte balance).
It is based on routine blood analysis and is powered by both proprietary machine learning and public algorithms, and provides highly accurate primary diagnostic information, including the likelihood of a wide range of electrolyte imbalance-related diseases, e.g. hypocalcemia, hypermagnesemia or hyponatremia, among others, and provide comprehensive information.
It is based on the combination of corrected calcium, corrected chloride, corrected magnesium, corrected potassium, corrected sodium, calcium/phosphate ratio and calcium/magnesium ratio.
It is an Evidence Based Laboratory Medicine (EBML) test developed not only in accordance with the guidelines of the American Association of Clinical Endocrinology (AACE) and the National Kidney Foundation (NKF), but also incorporating the latest scientific findings.
Screening recommendations
The United States Preventative Services Task Force (USPSTF) does not include any recommendations for screening for electrolyte imbalances.
However, Kience Inc. recommends the Venient Fx Hydroelectrolytic Metabolism Comprehensive test to treat patients with symptoms, signs or suspicion of disease: acute kidney injury (AKI), chronic kidney disease (CKD), drug-induced dyselectrolytemia, dehydration (i.e. prolonged vomiting and diarrhea), adrenal pathology, tubular and non-tubular renal disease, hypoparathyroidism, excessive use of laxatives, primary polydipsia, or second- or third-degree burns, among others.
Intended Use
The target population for the Venient Fx Hydroelectrolytic Metabolism Comprehensive test is patients with symptoms, signs or suspicion of disease: acute kidney injury (AKI), chronic kidney disease (CKD), drug-induced dyselectrolytemia, dehydration (e.g. e.g. e.g., prolonged vomiting and diarrhea), adrenal pathology, tubular and non-tubular renal disease, hypoparathyroidism, excessive use of laxatives or diuretics, primary polydipsia, or second- or third-degree burns.
Sample Clinical Vignette
A 78-year-old male with a previous antecedents of hypertension and heart failure with low ejection fraction that requires diuretics, presented for medical evaluation after a 1-week history of nausea, general malaise, headache and drowsiness. Physical exam revealed low blood pressure (85/40 mmHg), mild dehydration, mild bradypsychia and chronic edema of the lower limbs. Serum is submitted to detect ion-balance disorders related with the use of diuretics.
Required Laboratory Determinations
Serum Electrolytes —Bicarbonate, Calcium, Chloride, Magnesium, Phosphate, Potassium, Sodium—; Serum Proteins —Albumin—; Other Serum Analytes —Glucose—.