Venient Cx Health Check Comprehensive - Female

Test Description

Venient Cx Health Check Comprehensive is a non-invasive test (only requires blood and urine samples) for a comprehensive assessment of major complex functions, body systems and the whole metabolism given that many diseases or pathologies have a multifaceted component that makes them sometimes difficult to diagnose. It is based on a routine blood and urine analysis and it is powered by both public and proprietary machine learning (ML) algorithms and checks up to 303 non-malignant diseases linked to the major complex functions, body systems and the whole metabolism, with the highest prevalence in the population, many of which are considered risk factors for cancer. This test calculates and quantifies the onset of some diseases years in advance, based on the results of clinical data, laboratory tests and lifestyle habits. Thanks to the information provided on a personalized basis, the extensive report will suggest the best option to take corrective measures to avoid the natural course of both non-malignant diseases and cancer. The Venient Cx Health Check Comprehensive test covers: hematologic system (erythrocytes and iron transport function; iron storage function; immune cells system; and platelet function), coagulation function, cardiovascular system (anthropometric indicators; atherogenic indices, and vascular age), endocrinologic system (glucose metabolism and pancreatic endocrine function, thyroid function and hypothalamic-pituitary axis; parathyroid function; vitamin D and vitamin B12 absorption); gastrointestinal tract (including colorectal health) and liver (including bile-pancreatic exocrine function); genitourinary system (renal function; hydroelectrolytic metabolism; uric acid metabolism and prostate diseases in men, and ovarian diseases in women) as well as the systemic inflammatory response.

United States Preventative Services Task Force (USPSTF) screening recommendations

Currently, there is no USPSTF (United States Preventative Services Task Force) recommendation for "all medical" screening, and there is no commercially available FDA-cleared solution in the market.

Intended Use

Non-overweight women aged 40 onwards, annually and overweight or obese men aged 30 onwards, annually.

Sample Clinical Vignette

A 40-year-old female with sedentary lifestyle, smoker with an accumulated dose of 20 packs/year, on daily birth control pills, and several cardiovascular risk factors (hypertension, stroke and cancer) in first-degree relatives, presented for general medical check-up.

Required Laboratory Determinations

Hemogram —Red Blood Cell Count, Hemoglobin, Hematocrit, Erythrocyte Sedimentation Rate (ESR)—; Red Blood Cell Indices —Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Red Cell Blood Distribution Width (RDW)—; Leukocyte Count —Total Leukocytes Absolute, Total Neutrophil Absolute, Total Lymphocyte Absolute, Total Monocyte Absolute, Total Eosinophil Absolute, Total Basophil Absolute—; Platelets —Total Platelet Count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW)—; Coagulation —Prothrombin Time (PT), Activated Partial Thromboplastin Time (aPTT)—; Serum Antibodies —Antinuclear Antibody (ANA), Cyclic Citrullinated Peptides Antibodies (Anti-CCP), H. pylori IgG Antibodies, Rheumatoid Factor (RF)—; Serum Electrolytes —Calcium, Chloride, Magnesium, Phosphate, Potassium, Sodium—; Serum Proteins —Albumin, Apolipoprotein A1 (ApoA1), Apolipoprotein B (ApoB), High Sensitivity C-Reactive Protein (hs-CRP), Ferritin, Globulin, Lipoprotein (a), Total Protein—; Serum Hepatic Enzymes —Amylase Total, Amylase Pancreatic, Creatine Kinase (CK), Lipase, Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Gamma Glutamyl Transferase (GGT), Lactate Dehydrogenase (LDH)—; Serum Sterols & Fatty Acids —Total Cholesterol, HDL-Cholesterol, Cholesterol non-HDL, LDL-Cholesterol, VLDL-Cholesterol, Triglycerides—; Serum Hormones —Estradiol, Follicle-Stimulating Hormone (FSH), Insulin, Parathyroid Hormone intact (PTHi), Thyroid-Stimulating Hormone (TSH), Sex Hormone-Binding Globulin (SHBG), Thyroxine Free (T4 Free), Testosterone—; Serum Tumor Markers —Alpha Fetoprotein (AFP), Human Chorionic Gonadotropin - Beta Fraction (beta-hCG), Carbohydrate Antigen 19.9 (CA 19.9), Carbohydrate Antigen 125 (CA 125), Carcinoembryonic Antigen (CEA)—; Serum Vitamins —Vitamin B12, Vitamin D 25-OH Total—; Other Serum Analytes —Bilirubin Total, Bilirubin Direct, Bilirubin Indirect, Serum Creatinine, Glucose, Glycated Hemoglobin (HbA1c), Serum Iron, Urea, Blood Urea Nitrogen, Uric Acid—; Other Urine Analytes —Urine Albumin, Urine Creatinine—; Urinalysis —Density, pH, White Blood Cells, Nitrites, Protein, Glucose, Ketones, Urobilinogen, Urobilin, Red Blood Cells, Urine Sediment—.