Venient Cx Health Check Comprehensive - Male
Test Description
Venient Cx Health Check Comprehensive is a disruptive, non-invasive test for a comprehensive assessment of major functions, body systems and metabolism as a whole given that many diseases or pathologies have a multifaceted component that makes them sometimes difficult to diagnose.
It is based on routine blood and urine analysis and is powered by both proprietary machine learning and public algorithms, and tests for up to 303 non-malignant diseases related to major functions, body systems and metabolism as a whole, with higher prevalence in the population, many of which are considered risk factors for cancer.
This test estimates and quantifies the onset of some diseases years in advance, based on the results of clinical data, laboratory tests and lifestyle habits. Thanks to the information provided in a personalized way, the extensive report will suggest the best option for taking corrective measures to prevent the natural course of both non-malignant diseases and cancer.
The Venient Cx Health Check Comprehensive test covers:
- Hematologic system (erythrocyte and iron transport function, iron storage function, immune cell system and platelet function).
- Coagulation function.
- Cardiovascular system (anthropometric indicators, atherogenic indices and vascular age).
- Endocrine system (glucose metabolism and pancreatic endocrine function, thyroid function and hypothalamic-pituitary axis, parathyroid function, vitamin D and vitamin B12 absorption).
- Gastrointestinal tract (including colorectal health) and liver (including biliary-pancreatic exocrine function).
- Genitourinary system (renal function, water-electrolyte metabolism, uric acid metabolism, prostate disease in men and ovarian disease in women).
- Systemic inflammatory response.
Screening recommendations
The United States Preventative Services Task Force (USPSTF) does not include any recommendations for screening for alterations related to major body functions, systems and metabolisms as a whole, and there is no FDA-approved commercial solution on the market.
However, Kience Inc. recommends the Venient Cx Health Check Comprehensive (Male) to screen men 40 years of age or older who are not overweight, annually, and men 30 years of age or older who are overweight, annually.
Intended Use
The target population for the Venient Cx Health Check Comprehensive (Male) is men 40 years of age or older who are not overweight, annually, and men 30 years of age or older who are overweight, annually.
Sample Clinical Vignette
A 46-year-old male with sedentary lifestyle, smoker with an accumulated dose of 20 packs/year, with a diet based on carbohydrates and low on vegetables or fruits, and several cardiovascular risk factors (hypertension, stroke and cancer) in first-degree relatives, presented for general medical check-up.
Required Laboratory Determinations
Hemogram —Red Blood Cell Count, Hemoglobin, Hematocrit, Erythrocyte Sedimentation Rate (ESR)—; Red Blood Cell Indices —Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Red Cell Blood Distribution Width (RDW)—; Leukocyte Count —Total Leukocytes Absolute, Total Neutrophil Absolute, Total Lymphocyte Absolute, Total Monocyte Absolute, Total Eosinophil Absolute, Total Basophil Absolute—; Platelets —Total Platelet Count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW)—; Coagulation –Prothrombin Time (PT), Activated Partial Thromboplastin Time (aPTT)—; Serum Antibodies —Antinuclear Antibody (ANA), Cyclic Citrullinated Peptides Antibodies (Anti-CPP), H. pylori IgG Antibodies, Rheumatoid Factor (RF)—; Serum Electrolytes —Calcium, Chloride, Magnesium, Phosphate, Potassium, Sodium—; Serum Proteins —Albumin, Apolipoprotein A1 (ApoA1), Apolipoprotein B (ApoB), High Sensitivity C-Reactive Protein (hs-CRP), Ferritin, Globulin, Lipoprotein (a), Total Protein—; Serum Hepatic Enzymes —Amylase Total, Amylase Pancreatic, Creatine Kinase (CK), Lipase, Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Gamma Glutamyl Transferase (GGT), Lactate Dehydrogenase (LDH)—; Serum Sterols & Fatty Acids —Total Cholesterol, HDL-Cholesterol, Cholesterol non-HDL, LDL-Cholesterol, VLDL-Cholesterol, Triglycerides—; Serum Hormones —Estradiol, Insulin, Parathyroid Hormone intact (PTHi), Thyroid-Stimulating Hormone (TSH), Sex Hormone-Binding Globulin (SHBG), Thyroxine Free (T4 Free), Testosterone—; Serum Tumor Markers —Alpha Fetoprotein (AFP), Carbohydrate Antigen 19.9 (CA 19.9), Carcinoembryonic Antigen (CEA), Prostate-Specific Antigen Total (PSA Total), Prostate-Specific Antigen Free (PSA Free)—; Serum Vitamins —Vitamin B12, Vitamin D 25-OH Total—; Other Serum Analytes —Bilirubin Total, Bilirubin Direct, Bilirubin Indirect, Serum Creatinine, Glucose, Glycated Hemoglobin (HbA1c), Serum Iron, Urea, Blood Urea Nitrogen, Uric Acid—; Other Urine Analytes —Urine Albumin, Urine Creatinine—; Urinalysis —Density, pH, White Blood Cells, Nitrites, Protein, Glucose, Urobilinogen, Urobilin, Red Blood Cells, Urine Sediment—.